姚昌林

姚昌林 讲师

Email：cyao1992@ldu.edu.cn

教育经历：

2015.09-2021.06 山东大学 晶体材料研究所 材料学 工学博士

2018.10-2020.10 美国威斯康辛麦迪逊分校  访问学者  

2011.09-2015.06 济南大学 材料科学与工程学院 学士

工作经历：

2025.03-至今：鲁东大学集成电路学院

2021.12-2025.03：鲁东大学物理与光电工程学院

研究领域：

有机晶体的成核与生长机制

小分子药物晶体结构的主动设计及调控

药物分子晶体结构与性质研究

承担研究课题：

鲁东大学人才引进项目， 2021.12-2026.12，主持，在研

山东省自然基金青年项目（ZR2023QB252），2024.01-2026.12，主持，在研

山东省大学生创新创业项目

学术论文：

相关研究成果发表在J. Am. Chem. Soc, J. Phys. Chem. Lett., ACS Appl. Mater. Interfaces, Cryst. Growth Des, CrystEngComm, J. Pharm. Sci.等药物结晶主流期刊，近五年论文及发明专利：

(1) Changlin Yao*; Huimin Li; Peizuo Han; Lei Wang*; Xutang Tao; Melt Crystallization of Piroxicam Polymorphism: Nucleation and Growth Kinetics, and Polymorphic Selectivity Mechanism, Commun. Chem., 2025, Under Review (SCI 二区， 通讯作者)

(2) Peizhuo Han, Lei Wang*, Huimin Li, Changlin Yao*, et al. The New Cocrystal of Molnupiravir-Caprolactam Discovered by Melt Crystallization with Improved Tableting Properties. Int. J. Pharm. 2025, Submitted. (SCI 二区Top， 通讯作者)

(3) Zhiqiang Zhang, Yanpu Zheng, Changlin Yao*, et al. Revealing the underlying crystallization mechanism of perovskite crystals affected by additives with a typical surfactant span 20. Journal of Alloys and Compounds, 2025, 1010: 177263 (SCI 二区top， 通讯作者)

(4) Jiaoyan Xu#; Changlin Yao#*; Shufang Zhang; Xiaodong Zou; Yue Gui; Lei Wang; Hongyi Xu ; Polyethylene Glycol-Assisted Melt Crystallization of Two New Piroxicam Polymorphs Revealed by 3D Electron Diffraction, Crystal Growth Design, 2024, 24(17): 7298-7305 (SCI 二区, 通讯作者)

(5) Peizhuo Han; Lei Wang; Shuhong Song; Changlin Yao*; Xutang Tao; Guanying Xie; Huimin Li; Yaqian Qu; Hongshuai Wang; Zeliang Gao; Yanyan Sun; Huachang Wu; Weiguo Song ; Polymorphs and Solvates of Molnupiravir: Crystal Structures and Solid Forms Transformation Analysis, Crystal Growth Design, 2024, 24(11): 4758-4769 ((SCI 二区，通讯作者)

(6) Kangning Sun; Peizhuo Han; Changlin Yao*; Yaning Zhao; Chuanchi Zhang; Yao Zhang; Jingke Jiang; Lei Wang ; Surface Accelerates Crystal Nucleation: The Case of Molnupiravir, Crystal Growth Design, 2024, 24(15): 6413-6420 (SCI 二区，通讯作者)

(7) Changlin Yao; Shufang Zhang; Lei Wang; Xutang Tao; Recent Advances in Polymorph Discovery Methods of Organic Crystals, Crystal Growth Design, 23, 2023, 637-654. (SCI 二区, 第一作者, 通讯作者)

(8) Changlin Yao; Lei Wang; Xinyuan Wang; Xutang Tao ; Size-dependent solution-mediated phase transformation of piroxicam monohydrate particles, CrystEngComm, 2021, 23: 2928-2932 (SCI 二区,第一作者)

(9) Changlin Yao; Lei Wang; Yue Gui; Shigang Ruan; Ilia A. Guzei; Yingdi Jin; Guangxu Sun; Lian Yu ; Polymorphism of Piroxicam: New Polymorphs by Melt Crystallization and Crystal Structure Prediction, Crystal Growth & Design, 2020, 20(12): 7874-7881 (SCI 二区, 第一作者 )

(10) Changlin Yao; Yifan Li; Wang Lei; Shuang Song; Bo Li; Yang Liu; Xutang Tao. Tuning the Solution-Mediated Concomitant Phase Transformation Outcome of the Piroxicam Monohydrate by Two Hydroxyl-Containing Additives: Hydroxypropyl Cellulose and H2O. Crystal Growth & Design. 2019, 19, 583-590. (SCI 二区, 第一作者 )

(11) 姚昌林，一种吡罗昔康新晶型及其制备方法和应用，申请号：202410324354， 2024

近五年合作论文：

(1) Yaqian, Qu; Changlin Yao et al., Inhibition Efficiency of Cholesterol Monohydrate Crystallization by Linoleic Acid and Ethyl Linoleate. Cryst. Growth Des. 2025.

(2) Huimin Li; Lei Wang*; Xin Ye; Changlin Yao; Shuhong Song; Yaqian Qu; Jinke Jiang; Hongshuai Wang; Peizhuo Han; Yang Liu; Xutang Tao*, Efficient Screening of Pharmaceutical Cocrystals by Microspacing In-Air Sublimation, J. Am. Chem. Soc., 146, 2024, 11592-11598.

(3) Hongshuai Wang; Lei Wang*; Guanying Xie; Changlin Yao; Shuhong Song; Huimin Li; Yaqian Qu; Peizhuo Han; Zelaing Gao; Xutang Tao*, Solvates and Polymorphs of Baloxavir Marboxil: Crystal Structure and Phase Transformation Study, Cryst. Growth Des., 24, 2024, 3399-3409.

(4) Huimin Li; Lei Wang*; Guanying Xie; Changlin Yao; Shuhong Song; Yaqian Qu; Peizhuo Han; Hongshuai Wang; Yanyan Sun; Huachang Wu; Xutang Tao*, Cocrystals of Favipiravir: Improved Physicochemical Properties and Solution Stability Study, Cryst. Growth Des., 23, 2023, 8656-8669.

(5) Guanying Xie; Lei Wang; Dianxing Ju; Changlin Yao; Xinyuan Wang; Shuhong Song; Yaqian Qu; Huimin Li; Xutang Tao, Thermochromism Perovskite (COOH(CH2)3NH3)2PbI4 Crystals: Single-Crystal to Single-Crystal Phase Transition and Excitation-Wavelength-Dependent Emission. J. Phys. Chem. Lett. 2022, 13, 214-221.

(6) Guanying Xie; Lei Wang; Peizhou Li; Shuhong Song; Changlin Yao; Shanpeng Wang; Yang Liu; Zhen Wang; Xinyuan Wang; Xutang Tao, Low-Dimensional Hybrid Lead Iodide Perovskites Single Crystals via Bifunctional Amino Acid Cross-Linkage: Structural Diversity and Properties Controllability. ACS Appl. Mater. Interfaces. 2021, 13, 3325-3335.

(7) Xinyuan Wang; Lei Wang; Changlin Yao; Guanying Xie; Shuhong Song; Huimin Li; Yaqian Qu; Xutang Tao, Novel Formulations of the Antiviral Drug Favipiravir: Improving Permeability and Tabletability. Cryst. Growth Des. 2021, 21, 3807-3817.

(8) Shang Song; Lei Wang; Changlin Yao; Zhen Wang; Guanying Xie; Xutang Tao, Crystallization of Sulfathiazole in Gel: Polymorph Selectivity and Cross-Nucleation. Cryst. Growth Des. 2020, 20, 9-16.

(9) Zexin Wu; Lei Wang; Changlin Yao; Shang Song; Xinyuan Wang, Co-Amorphous Telmisartan-Pimelic Acid with Improved Solubility. Mater. Sci. Forum 2020, 993, 776-784.